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Englisch > Deutsch: Artikel aus med. Fachzeitschrift, 3 Seiten
Englisch > Deutsch: Artikel aus med. Fachzeitschrift
Sehr geehrte Damen und Herren,
ich möchte einen englische Artikel ins Deutsche übersetzt haben(3 Seiten). Von diesem PDF möchte ich nur Introduction, Egebnisse nur Texs (ohne Diagramme oder Tabellen) und Discussion. Da ich mehrere Artikeln habe möchte ich gerne Vorher ein pauschalpreis wissen. Keine 0,05 angaben.
Beispieltext:
The expression of the pro-inflammatory monocyte/
macrophage-derived cytokines, such as IL-1, IL-6, and
TNFa is also regulated following morphine administration.
Several laboratories have reported evidence which
shows that endogenous opioid administration leads to
the modulation of cytokine expression. Apte et al.
[50,51] have shown that endogenous endorphins and
enkephalins increase IL-1 production. Studies reported
by Roy et al. [52] suggest that morphine can synergize
with LPS to augment the production of both IL-6 and
TNFa. In a recent study reported by Wang et al. [53]
using a murine model of Streptococcal pneumoniae infection,
chronic morphine administration impairs resistance
to infection. Furthermore, in the morphine-treated animals,
there was a significant decrease in the levels of
TNFa, IL-1, and IL-6 in the bronchoalveolar lavage fluid.
It appeared that the impaired cytokine levels, together
with reduced levels of the chemokines CXCL2 and
CXCL1, and impaired galectin-3 in the alveolar space,
resulted in a reduction in the migration of protective neutrophils
to the site of infection [53]. These results are particularly
interesting when viewed in the context of earlier
results showing that the reduced capacity of splenocytes
from morphine-treated mice to produce antibody
ex vivo could be reversed by the addition of exogenous
IL-1, IL-6 or IFN-c [54]. The latter results suggest impairment
in the levels of IL-1 and/or IL-6, and would be
entirely consistent with the results of Wang et al. [53]
which suggest that morphine inhibits the production of
some of the pro-inflammatory monocyte/macrophagederived
cytokines. However, studies carried out with
human peripheral blood cells (described below) to determine
the effects of morphine on pro-inflammatory chemokines
appear to suggest that opioid administration does
not induce a universal impairment in pro-inflammatory
cytokine expression.
Studies on the KOR
Specialization required
Medical
Language pair(s)
English
> German
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