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159 months ago

Claudia Botero (a guest user) asked this question:

This question has already been answered and rated. Therefore, no new answers can be given.

159 months ago

Fernando Soni   wrote:

integrina

My comment:

Se usa esa palabra médicamente.
Son heterodímeros obligados que participan en la unión de las células con la matriz extracelular.

159 months ago

Adriana Dosal   wrote:

integrina

My comment:

Las integrinas son una superfamilia de glicoproteínas que participan mayoritariamente en la unión de las células con la matriz extracelular, aunque hay algunas que también participan en la unión célula-célula. Están presentes en la superficie celular en elevadas concentraciones.

My references:

http://es.wikipedia.org/wiki/Integrina (Spanish)
http://en.wikipedia.org/wiki/Integrin (English)

Comments by other colleagues on this answer:

159 months ago

   wrote:

Totalmente de acuerdo con lo propuesto

159 months ago

Adriana Dosal   wrote:

Muchas gracias Bertrand.

159 months ago

S_bogdAn   wrote:

infectividad de células tumorales a través de unión a integrina ......

My comment:

Regarding cells in the human body, integrins are receptors that connect and posses an attachment membrane between a cell and the tissues that surround it. Integrins transduce information from the ECM(extracellular matrix) to the cell as well as reveal the status of the cell to the outside, allowing rapid and flexible responses to changes in the environment, for example to allow blood coagulation.Integrins work alongside other proteins such as cadherins, immunoglobulin superfamily cell adhesion molecules, selectins and syndecans to mediate cell–cell and cell–matrix interaction and communication. Integrins bind cell surface and ECM components such as fibronectin, vitronectin, collagen, and laminin. To answer the question in the context given, "tumor cell infectivity where the transmembrane receptors that mediate the attachment between a cell and the tissues that surround it are located"

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